ScreenFlow is one software that I love using, not only does it capture the action of the computer screen as you are using it you can do some pretty good editing afterwards too. Find out more.
If you are making a movie and you are talking to the camera then you need VideoCue which is a teleprompter and then on top as a bonus gives you chromakey, titling and some really good transitions. Find out more.
Mozy Back up